Minati Satpathy

 

Research Scientist II

Research Interests:

  • Ovarian cancer
  • Nanotechnology
  • Targeted drug delivery (siRNA, microRNA)
  • Molecular imaging
315 Ferst Drive NW
Atlanta, GA-30332, U.S.A.
Office: IBB 3213
Email: minati(dot)satpathy(at)biology(dot)gatech(dot)edu
Phone: 404.385.6631
Fax: 404.894.2219
Professional Experience
Research Scientist II School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA July 2014 – Present
Research Associate Department of Oncological Surgery, Emory University, Atlanta, GA, USA. 2009 – 2014
Post-Doctoral Research Associate Oncology and Hematological Division, Indiana University-Purdue University at Indianapolis, (IUPUI), Indianapolis, IN, USA. 2005-2009
Post-Doctoral Fellow School of Optometry, University at Bloomington, IN, USA. 2000-2005

Education
Ph.D., Biochemistry University of Delhi, India 1998

Publications
  1. Satpathy, M ; Wang, L; Zielinski, R; Qian, WP ; Lipowska., M Capala, J; Lee, GY; Xu, H; Wang, Y   Mao, H and Yang, L. (2014): Active Targeting Using HER-2-affibody-conjugated Nanoparticles Enabled Sensitive and Specific Imaging of Orthotopic HER-2 Positive Ovarian Tumors Small. 10(3):544-55.
  2. Lei, X, Satpathy, M., Zhao, Q, Qian, W., Yang, L and Jiang.,H. (2014) Photoacoustic and fluorescence tomography of HER2/neu positive ovarian cancers using receptor-targeted nanoprobes in an orthotopic human ovarian cancer xenograft model. Nanomedicine 10(3):669-77).
  3. Lee, GY, Qian,W, Wang, L, Wang,Y, Staley,CA, Satpathy, M,  Nie, S, Mao,H and Yang,L. (2013): Theranostic nanoparticles with controlled release of Gemcitabine for targeted therapy and MRI of pancreatic cancer. ACS Nano Mar 26;7(3):2078-89.
  4. Satpathy,M, Shao M, Emerson, R., Donner, D. and Matei D (2009) Tissue    Transglutaminase Regulates MMP-2 in Ovarian Cancer by Modulating CREB Activity. J Biol Chem Jun 5; 284 (23):15390-9.
  5. Shao M, Cao L, Shen C, Satpathy M, Chelladurai B, Bigsby RM, Nakshatri H, Matei D.(2009). Epithelial-to-Mesenchymal Transition and Ovarian Tumor Progression Induced by Tissue Transglutaminase. Cancer Res 69: 9192-9201.
  6. Satpathy,M  Cao L, Pincheira, R, Emerson, R., Bigsby, R., Nakshatri H, Matei D (2007) Enhanced peritoneal ovarian tumor dissemination by tissue transglutaminase Cancer Res, Aug 1; 67: 15.
  7. Matei D, Satpathy M, Cao L, Lai YC, Nakshatri H, Donner DB (2007) The platelet derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells. J Biol Chem. Jan 5;282(1):445-53.
  8. Cao L., Petrusca, D, Satpathy, M, Nakshatri H, Petrache, I, Matei, D. (2008) Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin induced apoptosos by activating NFkB. Carcinogenesis 29(10):1893-900.
  9. Ramachandran, C, Satpathy, M., Mehta, D and Srinivas, S.P. (2008) Forskolin induces Myosin Light Chain dephosphorylation in Bovine Trabecular Meshwork Cells. Curr Eye Res. Feb; 33(2):169-76.
  10. Guo,Y. Satpathy,M.,Wilson, G and Srinivas S.P. (2007) Benzalkonium chloride induces dephosphorylation of myosin light chain in cultured epithelial cells.IOVS, 48(5):2001-8.
  11. Guo. Y, Ramachandran, C, Satpathy, M., Srinivas, S.P. (2007) Histamine-induces Myosin Light Chain Phosphorylation Breaks Down the Barrier Integrity of Cultured Monolayers of Corneal Epithelial Cells. Pharm Res. Oct; 24(10):1824-33.
  12. Srinivas, S.P., Satpathy, M. Guo,Y, and Anandan, V (2006) Histamine-induced phosphorylation of the regulatory light chain of myosin II disrupts the barrier integrity of corneal endothelial cells. IOVS 47(9):4011-8.
  13. Satpathy, M., Gallagher, P., Jin, Y. and Srinvas S.P. (2005) Extracellular ATP opposes thrombin-induced myosin light chain phosphorylation and loss of barrier integrity in corneal endothelial cells. Exp Eye Res.  Aug;81(2):183-92.
  14. Satpathy, M., Gallagher, P., Lizotte-Waniewski, M. and Srinivas S.P. (2004) Thrombin-induced phosphorylation of the regulatory light chain of myosin II in cultured bovine corneal endothelial cells. Exp Eye  Res.79 (4): 477-486.
  15. Srinivas, S.P., Satpathy, M., Gallagher, P., Larivière, E. and Van Driessche W. (2004) Adenosine induces dephosphorylation of myosin II regulatory light chain in cultured bovine corneal endothelial cells. Exp Eye Res. 79(4): 543-551.
  16. Srinivas, S.P., Maertens,C., Goon L.H.,Goon L., Satpathy, M., Yue, B.Y.J.T., Droogmans, G. and Nilius,  B. (2004) Volume-regulated anion channels in cultured bovine trabecular meshwork cells Exp Eye Res. Jan;78(1):15-26. 
Book Chapters
  • Satpathy, M., Zhou, H and Yang, L (2013): Image-guided cancer treatment using theranostic nanoparticles. A chapter in “Nanotechnology in Modern Medical Imaging and Interventions” by Nova Science Publishers. Inc. USA.
  • Satpathy, M., Zielinski, R., Lyakhov, I and Yang, L (2015): Optical Imaging of Ovarian Cancer Using HER-2 Affibody Conjugated Nanoparticles. A chapter in “Methods in Molecular Biology” 1219: pp 171-85, Springer Science Publishers, New York, USA.