RNAi-Chemo Tag Team Slams Ovarian Cancer

Genetic Engineering & Biotechnology News (November 7, 2016)

A more sure-footed partner for chemotherapy has been developed by scientists based at the Georgia Institute of Technology. These scientists, led by John McDonald, Ph.D., have devised a functionalized nanohydrogel siRNA delivery system. This system, in a mouse model of ovarian cancer, succeeded in honing in on ovarian tumors and sensitizing them to the chemotherapeutic agent called cisplatin. Together, the siRNA and the cisplatin dramatically shrank or even eliminated the tumors. (full story..)